The Oncotarget journal came into formation in the year 2010. It mainly focuses on oncology, a part of medicine that deals with arrest, examination, and treatment of cancer. However, in the recent years, it has developed to cover the non-oncological publication. Its chief editors are Andrei V. Gudkov and Mikhail Blagosklonny who both work at Roswell Park Institute.
Oncotarget usually posts its release online on a free access site to enable efficient and quick viewing of their articles. Mainly, Oncotarget publish Oncology papers, but due to great success, they have diversified the journal to cover other fields like cardiology, microbiology, pharmacology and neuroscience.
According to Thomson Reuters JCR Impact Factor, they have ranked number one since the year 2011 to the present time, which is a great accomplishment for the journal on ncbi.nlm.nih.gov. They base the success to their well-organized methods of publishing; they have the right editors with a great passion for the topics. Onctotarget is readily available via the Facebook, Twitter, YouTube, LinkedIn and Google +; this is in the spirit of reaching more audience globally.
Research on relationship between E-cigarette and gum tissue
E-cigarette refers to a battery operated device that causes oral danger when metal heating element evaporates. It denatures the formation of the Deoxyribonucleic acid(DNA)in that it can change the appearance of the protein, change its structure or denaturing overall tithe result is rupturing or inhibiting its intended function. In the mouth, it causes the inflammation of the gum. The proteins do not combine as intended.
It further states that its effect resembles that of smoking in the manner in which they destroy the periodontal cells. The result of the research discouraged any exposure to the metal heating elements as they posed more threat to the human body.
MET Amplification as potential therapeutic target in gastric cancer
It stated that the patients were responding positively to cytotoxic chemotherapy. Though no exact establishment is reached on dovepress.com, the combination of CDDPinclusive of 5 fluorouracil does help in new cases of gastric cancer.
The research done on 327 victims showed that 260 patients who were the first treated with fluoropyrimidine and platinum chemotherapy had the better chance of survival. 16 showed FGF Amplification depended on the age factor, Borman grade activities, Extra-abnormal lymph bone, and metastases.
The result On Oncotarget revealed that independent prognostic predictor in patients worked only in the new cases while in the earlier cases it did not work. Nevertheless, to say there was no impact after being introduced in advanced stages of gastric cancer would be erroneous.